The most common and effective treatment for wet age-related macular degeneration (wet AMD) is called anti-VEGF therapy. Your doctor gives you this therapy through an injection directly into your eye. How often you need these injections depends on your case of wet AMD. It could be as often as every few weeks or as far apart as every few months. Here’s what to know about this treatment. VEGF stands for vascular endothelial growth factor. It’s a protein that promotes the growth of blood vessels when your body needs them. When you have macular degeneration, some new blood vessel growth isn’t healthy for your eyes. They tend to be weak and grow in places that harm instead of help your vision. Anti-VEGF therapy keeps VEGF from making new blood vessels grow in your eye, which in turn can help curb fluid leakage in your retina. All four medications stop blood vessel growth, though they do it in slightly different ways. They’re similarly effective and come with similar risks. Your doctor will help you decide which is best for you. The main side effect risks are infection or inflammation in the eye, bleeding into a gel inside your eye called the vitreous gel, and retinal detachment.
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